Kidney

HaemoScan has a long history developing and performing kidney biomarker assays in collaboration with the Nephrology department of the University Medical Centre Groningen.

 

We offer the following kidney injury markers:

 

N-acetyl-glucoseaminidase (NAG)

N-acetyl-glucoseaminidase is excreted into the urine following injury to the tubular system of the kidney. This injury may occur after renal ischemia or may be induced by an inflammatory reaction. A quantitative measure of tubular damage can be obtained after simultaneous measurement of urea, to correct for dilution. NAG is determined by means of a substrate conversion assay. Under appropriate conditions, NAG present in a urine sample converts a chromogenic substrate. After development of the color the optical density is determined. The concentration [U/mL] is quantified by applying standards with known concentrations of the enzyme.