Blood Activation Research

HaemoScan is an expert centre to investigate how biomatarials, structures or pharmaceuticals interact with blood. We have developed assays to study the interaction with blood at all stages.
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Blood material interaction consists of an immune response and a haemostatic response. Both responses include protein and cell interaction and activation. Activation products can induce an inflammatory reaction and disturb haemostasis. This, in turn, can have consequences for the organs. To evaluate this effect we measure biomarkers indicating organ or tissue injury. HaemoScan thus evaluates complete blood interaction and its consequences with a device, pharmaceutical or (bio)material. Read more

Blood contacting medical devices


For research and development of medical devices haemocompatibility plays an important role for the selection of the proper biomaterial. HaemoScan has developed tests to give insight into the haemodynamic properties of the (bio)material.


ISO Certification


For quality assurance your final product has to be tested in accordance to ISO 10993-4: “Selections of test for interaction with blood.” We are specialized in selecting and performing the appropriate tests needed to meet those ISO standards.



Organ and tissue injury

For many years HaemoScan has been involved in evaluating the clinical application of medical devices, which has resulted in more than 150 publications. Some of these studies initiated the introduction of new devices such as membrane oxygenator, leucocyte depletion filters and the use of heparin coatings. In general these studies were designed for efficacy testing and/or comparison to other devices or techniques. The usage of large medical devices (such as the heart-lung machine) results in elevated plasma levels of kidney, brain and lung injury markers. Post marketing surveillance is necessary for certain types of medical devices, organ and tissue injury markers are very suitable to evaluate safety.
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