Acute phase proteins

Acute phase proteins

The acute phase response is induced by signals that travel through the blood from sites of injury or infection. Cytokines, such as TNF-alpha, IL-1, and IL-6 are responsible for induction of the acute phase response; they act on hepatocytes in the liver, inducing them to secrete acute phase proteins. Plasma concentrations can increase (positive acute phase proteins) or decrease (negative acute phase proteins) as a response to inflammation. Among acute phase proteins are many components of the complement system, and other proteins that function as opsonins, enhancing phagocytosis.

 

Common assays of acute phase proteins that we offer: